Certified Professional in IACUC Administration (CPIA) Practice Exam

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• What is the proper sequence for a designated member review by the IACUC?
• Which member type is emphasized for their input in IACUC meetings?
• How can one identify a hazardous area within a facility?
• Who is responsible for the ethical treatment of animals in research at an institution?
• What does the acronym IRAC stand for in the context of animal research?
• What should happen if an alternate member wishes to vote during a meeting?
• What does the IO need to ensure about the animal care program?
• Principal investigators are discouraged from advocating for animal reuse as a reduction strategy because it should not be a rationale for what?
• Regarding IACUC use of review outcomes such as "approval pending," "conditional approval," or "deferred," which of the following is false?
• Which statement about IACUC suspensions of animal activities is false?
• What is the role of the Institutional Official regarding animal-use projects?
• What is the primary mission of the Animal Welfare Information Center (AWIC)?
• Which organization is abbreviated as PHS?
• What is NOT included in the program review portion of the semi-annual IACUC evaluation?
• Which of the following is a required member of the IACUC?
• What aspect of animal care may be the focus of IACUC scrutiny?
• What is a key reason for having alternates in the IACUC?
• Which entity enforces the AWA?
• When should the IACUC and IO report a suspension?
• What is one responsibility of IACUC members concerning animal care protocols?
• In the case where a faculty member demonstrated a blood sampling procedure not approved by the IACUC, to whom must the noncompliance be reported?
• What authority must institutions provide to the Attending Veterinarian regarding veterinary care?
• Which members must be present for the IACUC to conduct business according to DoD regulations?
• What must the IACUC do if a concern is raised regarding animal care?
• What change was made to the Animal Welfare Act by the 1990 pet protection amendment?
• What are the main goals of the semi-annual evaluation of the IACUC?
• True or False: The VA rules are less strict compared to USDA/PHS rules.
• Which of the following is true regarding the dog exercise program mandated by USDA Animal Welfare Act regulations?
• How does OLAW define a suspension in relation to animal activities?
• In terms of animal welfare, what does the term 'warm-blooded animals' refer to?
• Which body requires the reporting of uncorrected significant deficiencies?
• Which of the following is NOT a requirement for IACUC minutes?
• On behalf of an institution, which individual is ultimately responsible for compliance with PHS Policy?
• Which transmission mode is not considered major for the herpes B-virus?
• Under what circumstances must USDA/APHIS be informed of a suspension of animal activities?
• What type of training should IACUC alternates receive?
• Which federal law mandates the PHS Policy?
• What is the meaning of the acronym IACUC?
• In the event of IACUC criticism, which action is suggested for the institution?
• Which statement best reflects the relationship between IACUC approval and animal work initiation?
• What does the Animal Welfare Act Regulations say about reporting violations?
• In the absence of IACUC approval, can any other body or official approve an animal protocol?
• What duty is NOT assigned to the IO by the Animal Welfare Act Regulations?
• Which infection poses a significant risk to a human fetus?
• Is a quorum necessary for the semi-annual evaluation according to AWAR?
• True or False: DoD requires its facilities to be accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC).
• What is the purpose of OHSP in research?
• Which of the following circumstances must be reported promptly to USDA?
• Do animal protocols need pre-review according to regulations?
• Which of the following does NOT need to be maintained by the IACUC?
• True or False: All required members of the IACUC must be voting members.
• What must a facility do if it is not able to meet the requirements for animal housing?
• Can the IACUC conduct formal business if a quorum is lost during a meeting?
• Which of the following is a key component of a post-approval monitoring program?
• What does the term primary enclosure mean?
• Is it permissible for federal employees to endorse products using their Government position or title?
• Which aspect of care is the attending veterinarian required to oversee according to AWA Regulations?
• Which agency requires an annual report of animals used categorized by pain/distress levels?
• What options do designated reviewers have during their review?
• PHS Policy __________ an occupational health and safety program for PHS-assured institutions.
• What is an indicator that a designated reviewer can begin their work?
• Why is it critical that IACUC members attend meetings regularly?
• How should IACUC minutes be structured to ensure transparency?
• Which statement about polling IACUC members is correct?
• What does the acronym AC refer to in the context of animal care and regulation?
• Can squirrel monkeys transmit herpesviruses to owl monkeys?
• What serves as a biological filter in the life support systems for aquatic animals?
• Which of the following statements is true regarding IACUC's triennial review of animal activities?
• According to the 8th edition of the Guide, what must institutions have in place regarding occupational health?
• What is the primary function of an Aquatic Life Support System?
• Does the VA require its Veterinary Associate (AV) to be present for the semiannual review?
• When using CO2 for euthanasia, what should be maintained after apparent death?
• Which department is chiefly involved in national defense matters?
• Should the veterinary medical staff evaluate the health status of newly received animals?
• Which area is expected to have the same standards and care as animal procedure rooms?
• Which agency is responsible for deciding if a federal employee has violated conflict of interest statutes?
• How detailed should the USDA-required annual review be?
• What level of authority must the IACUC have to fulfill its responsibilities?
• In research protocols, how should surgery on regulated animals be handled?
• In what aspect can the IACUC's authority be described?
• What type of practices does GLP refer to?
• When must all personnel performing animal procedures be properly trained?
• Who is responsible for appointing alternate members in the IACUC?
• To whom does the IACUC report if the progress toward correcting significant deficiencies is lacking?
• What is a necessary quality for the IACUC Chairperson regarding parliamentary procedure?
• Which of the following entities does NOT report directly to the IO?
• What does the term "Thermoneutral Zone" (TNZ) refer to?
• Which combination is required for IACUC members according to PHS policy?
• When conducting research outside of the United States, do DoD researchers need to comply with local regulations?
• What procedural action should be taken if an animal exhibits severe pain post-surgery?
• Which regulatory entity enforces the Animal Welfare Act?
• What action should be taken if an IACUC member has a direct financial interest in a protocol?
• What information is required in the report for deficiencies identified during IACUC evaluations?
• Under what circumstance would designated-member review result in a full committee review being called?
• Biosecurity measures in a research area may include which of the following?
• What organization is associated with enforcing PHS Policy?
• What is considered best practice for the IACUC Chairperson?
• Which of the following provides voluntary accreditation for animal care programs?
• Under what conditions would a semiannual report need to be submitted to OLAW?
• Do employees of VA non-profit research corporations have to follow the same conflict of interest statutes as federal employees?
• What role does the Institutional Official (IO) have regarding the semi-annual report?
• What constitutes a quorum in the IACUC context?
• True or False: The IACUC can extend protocol approval without a full committee review after the triennial review is due.
• How frequently must the IACUC evaluate the animal care program?
• Is it a requirement for IACUC members to have access to grant documents?
• Veterinarians providing clinical oversight should possess what qualifications?
• What should be avoided in the colloquial use of terms related to IACUC reviews?
• What outcome option is available in full committee review but not designated review of animal protocols?
• Which document outlines the importance of confidentiality for IACUC members?
• Which of the following outcomes is considered a valid response in a designated review?
• Flow Through systems in aquatic life support primarily rely on what type of water use?
• Which codes and policies emphasize animal research as a moral imperative?
• What is the correct usage of carbon monoxide in euthanasia?
• What should IACUC minutes allow for an outside observer to do?
• What organization is represented by the acronym AALAS?
• Do stocks held by a sector fund generally represent a disqualifying financial interest under 18 U.S.C. § 208?
• What is necessary for the IACUC to report a suspension effectively?
• Should alternate members be included on IACUC rosters submitted to OLAW?
• What should the Attending Veterinarian consult the IACUC on?
• Decentralization in research facilities can lead to increased exposure to disease agents due to what considerations?
• According to USDA regulations, failure to correct a significant deficiency must be reported within how many days by whom?
• What is considered a significant change to an animal use proposal?
• Which of the following types of drugs relieve pain?
• Which of the following statements regarding IACUC members is true?
• What is a potential disadvantage of a passive PAM program?
• Who is responsible for monitoring the expiration date of drugs stored in a procedure room?
• Who appoints the IACUC members?
• What best describes the required composition of a 5-member IACUC?
• Is it permissible for a non-affiliated member of the IACUC to be a veterinarian?
• Areas for quarantine, hazardous substance studies, and nonhuman primate rooms should be kept at ______________ pressure.
• What should be the state of animal drinking water according to specific animal requirements?
• Which definition best describes euthanasia according to AVMA guidelines?
• What are the four categories of protocol reviews?
• PHS institutional Assurance is approved for a maximum of how many years, while USDA registration is updated every how many years?
• If a significant deficiency is NOT corrected according to the IACUC semi-annual evaluation report, what is the proper course of action?
• Which is an example of appropriate enrichment for a guinea pig?
• What is the proper protocol for designated reviews by the IACUC?
• Who primarily oversees compliance with the Animal Welfare Act?
• What should a federal physician do before recruiting VA patients for a clinical study to ensure compliance with ethics statutes?
• What should non-scientist IACUC members do during meetings?
• What action should be taken if a research project is found to be in significant noncompliance?
• What should an IACUC member do if they do not understand a scientific protocol during a meeting?
• Feed and bedding should be:
• What does the acronym AWIC stand for?
• Which regulatory body mandates that the IACUC must have a Chairperson?
• What two components must be included in the IACUC's semi-annual self-evaluation?
• What is the primary purpose of the IACUC in the context of animal research?
• Which organization primarily focuses on public health and safety?
• Which disease is not easily transmitted to humans through animal bites?
• What must the IACUC ensure regarding alternatives to painful procedures?
• What is expected of designated reviewers regarding the consensus on a protocol?
• Which entity is responsible for enforcing the Health Research Extension Act?
• Who has the legal authority to sign the USDA registration form of a research institution?
• When conducting the facilities inspection portion of the semi-annual evaluation in compliance with both the USDA Animal Welfare Act Regulations and PHS Policy, the IACUC must include:
• Which policy prohibits IACUC members from voting on their own proposals?
• Who must review and sign the semi-annual report?
• What does the term "polling" refer to in the context of IACUC operations?
• What must be done regarding significant changes to animal protocols after IACUC approval?
• When should you stop using a sharps container?
• What must the IACUC do if a majority of a quorum votes to suspend research activities?
• What does NSF stand for in research funding?
• What is the acceptable range for maintaining dry-bulb temperatures according to HVAC standards?
• Is it mandatory for sanitary measures to be applied at least every two weeks?
• Which of the following is NOT a reason to seek agency advice on conflicts of interest?
• What does EPA stand for?
• What must be weighed when identifying humane endpoints in studies?
• What must be reported to AAALAC regarding the animal care and use program?
• Can the VA grant waivers for employees to participate in particular matters without disqualifying financial interests being substantial?
• What is the primary purpose of regulations in relation to statutes?
• Under which legislation are animals excluded from coverage, including Rattus and Mus?
• What is false regarding conditional approval in IACUC protocols?
• Which department is abbreviated as DOD?
• What is the relationship between primary reviewers and designated reviewers in IACUC practice?
• Is the floor space occupied by food bowls and enrichment devices considered part of the total floor space?
• At a minimum, what is required for animals regarding their space in enclosures?
• What happens if an IACUC is not properly constituted?
• If an institutional official halts an animal activity, can they reinstate it without IACUC involvement?
• Which statement about alternate IACUC members is false?
• Should the use of pesticides be recorded and coordinated with animal care staff?
• What can happen if a federal employee violates regulations?
• If multiple designated reviewers are involved and one calls for a full committee review, what is the outcome?
• Under what circumstance is the IV or IC injection of potassium chloride an acceptable euthanasia method?
• What must be taken into account regarding confidentiality and medical evaluations?
• When is a designated reviewers system typically used?
• Who is the Executive Agent for the Department of Defense Directive number 3216.1?
• What are the two criteria the IACUC should evaluate before suspending an animal activity?
• What does the Animal Welfare Act Regulations state regarding IACUC members reporting violations to USDA?
• Which body is specifically tasked with reviewing animal research protocols?
• Is the attendance of the Attending Veterinarian mandatory for the IACUC to conduct its business?
• Who typically holds the title of Principal Investigator in a research study?
• Which institutions are required to comply with the PHS Policy?
• What are the VA IACUC membership requirements based on?
• In collaborative animal use situations, what is necessary regarding responsibilities?
• Which military branch governs the DoD Veterinary Services Program?
• What does GLP stand for in the context of laboratory practices?
• Which agency is known as the FDA?
• What is not a required inclusion in the VA semiannual program review report?
• Which action is NOT permitted by the Institutional Official according to USDA Animal Welfare Act Regulations and PHS Policy?
• What primary aspect do institutional policies address regarding animal welfare?
• Which entity is required to release information under the Freedom of Information Act?
• Which statement accurately describes an expectation from IACUC regarding protocol compliance?
• What is the expected frequency for cleaning a procedure room?
• What are considered "significant changes" that require a review of an amendment?
• Are occupational health and safety programs intended to protect employees in animal facilities required to be the same at all institutions where research animals are housed?
• What does the term 'semiannual review report' refer to in DoD regulations?
• What is the mechanism of action of an overdose of barbiturates for euthanasia?
• What is the focus of IACUC's facility inspection component during evaluations?
• Can alternates participate in IACUC activities if their regular member is present?
• What are the two main components of the semi-annual evaluation process?
• What is a quorum of a committee?
• Dogs obtained from a Class B dealer may originate from which of the following sources?
• What are two review methods allowed by the USDA and PHS?
• Which statement best defines the role of the Attending Veterinarian in relation to animal care programs?
• Which statement about inhalant agents used for euthanasia is true?
• Which of the following is NOT a required element of the semi-annual report according to AWAR?
• Who is responsible for reporting infractions in DoD research?
• What is a mandatory requirement for the non-affiliated member within the IACUC according to the DoD?
• Which of these IACUC protocol review outcomes are recognized in the USDA Animal Welfare Act Regulations and PHS Policy?
• What is the purpose of having an effective IACUC?
• Regarding IACUC review outcomes, which statement is TRUE?
• In which situation is serum collection and storage valuable?
• The AWA Regulations require that the attending veterinarian must:
• What is the primary focus of IACUC training for personnel?
• Who serves on the IACUC by virtue of their employment status?
• What does the term 'silence' signify in the context of IACUC review processes?
• Who is responsible for oversight of the DoD animal use program?
• Which activity qualifies an animal for category E?
• As a VA employee, are you required to disclose intellectual property to the VA?
• What document oversees the responsibilities of the IACUC within an institution?
• The IACUC may suspend an activity only after?
• What is a key responsibility of IACUC members during meetings?
• Who must participate in the semiannual review according to VA rules?
• Who has the authority to stop animal activities in an institution?
• What determines cage space requirements for nonhuman primates as outlined in the Animal Welfare Regulations?
• During an IACUC meeting, what is necessary for documentation in the minutes regarding a withheld approval?
• What type of event must be reported as adverse regarding IACUC protocols?
• Can any veterinarian serve on the IACUC?
• What key aspect of semi-annual evaluations is emphasized by both USDA and PHS?
• Which agency's guidelines require compliance from institutions conducting animal research?
• Which factor is essential when designing HVAC systems for research facilities?
• Which statement about the CEO and IO is false?
• In best practices, how should IACUCs communicate the results of their investigations?
• Which hazard is addressed with the use of bite and scratch emergency kits?
• True or False: IACUC members cannot participate in the review of activities they are personally involved in.
• What statement is true regarding the effects of anesthetics?
• When conducting a semi-annual self-evaluation, how many IACUC members are needed?
• Which statement about the CEO and IO is FALSE?
• Which line of authority is responsible for submitting the annual report to OLAW?
• What authority does the Institutional Official (IO) have regarding previously approved animal activities?
• Which situation requires the full IACUC committee's review rather than Designated Member Review?
• How is a quorum defined in relation to conducting official IACUC business?
• What is a requirement for an IACUC to allow for modifications before granting approval?
• What responsibility does the IACUC have in relation to animal studies?
• What are the two IACUC review methods recognized by the USDA Animal Welfare Act Regulations and PHS Policy?
• In the VA system, who is involved in the appointment process for the IACUC?
• How frequently should biological safety cabinets be certified?
• What happens when all members agree to DMR during the decision-making period?
• Why should an IACUC consult with the Attending Veterinarian?
• What term refers to the physical structure that contains both the water and the animals used in research?
• Which of the following is not an IACUC activity?
• What does AAALAC stand for?
• If a significant deficiency is not corrected as per the IACUC timeline, what action must be taken?
• Which of the following statements reflects how institutions should prioritize animal care efforts?
• What action should be taken regarding unsanitary conditions identified in laboratories?
• Which of the following statements regarding the process of polling IACUC members via email is true?
• Which animal areas are required to be inspected?
• Which of the following statements is true regarding statutes?
• Where should the USDA annual report be sent?
• Under what circumstances is it acceptable to store food and chemicals in the same refrigerator?
• Which document specifies fines for IACUC members who violate confidentiality regulations?
• What should be the primary consideration when setting standards for animal care in a research facility?
• How are the best practices for designated reviews typically sequenced?
• Should agents designed to mask animal odors be used in housing facilities?
• Which of the following statements about an HVAC system is FALSE?
• What must the IACUC do if a temporary hold leads to a majority vote suspension?
• Which two institutional administrators are specifically dealt with in regulations?
• What is the full form of DHHS?
• In which scenario would the IACUC require a significant review process?
• A person supplying dogs to research is exempted from licensing with the USDA under which of the following conditions?
• Does every project have to undergo both annual and triennial reviews?
• In compliance with USDA regulations, the IACUC must inspect which areas?
• What is the primary goal of the IACUC in animal research settings?
• Who is responsible for ensuring that the amendments are reviewed before implementation?
• What should a PAM staff member do if they find serious noncompliance?
• What activity would disqualify an animal from USDA category D?
• Which of the following statements about euthanasia methods is incorrect?
• Who decides if a deficiency is classified as significant or minor?
• What is the initial process for designated-member review of new submissions?
• What is the required action if a significant deficiency is not corrected according to the IACUC semi-annual evaluation report?
• What is one requirement laid out by USDA regulations for IACUC members?
• Regarding inhalants, what precaution should be taken?
• Is it acceptable to hold excess equipment in a procedure room as long as the equipment is covered?
• Is a formal Post Approval Monitoring program required by PHS Policy?
• Can one alternate member serve for multiple regular members in an IACUC?
• Which of the following is NOT a criterion for the Attending Veterinarian?
• What is one of the primary focuses of AWIC?
• What is the general standard for details in IACUC minutes?
• What consequence can arise from violating ethics regulations?
• Which is NOT a main objective of the Guide?
• What happens if an institution experiences an adverse event related to its animal program?
• If the IACUC withholds approval, what must be included in the notification?
• Which regulatory body requires annual reviews?
• How long must animals be housed for an area to be included in the IACUC's semi-annual evaluation?
• If an investigator conducts category B, C, and D activities on the same animal, how should that animal be classified?
• In special circumstances, what is the determining factor for deviating from AVMA guidelines?
• How often must the IACUC meet according to the guidelines?
• Can the same pool of alternate members be used for multiple regular IACUC members?
• Is it ethically acceptable for a federal physician to accept a payment for a presentation on their research to a non-profit organization?
• Which is one of the key responsibilities of the IACUC?
• Which of these is not part of the acronym used by the entity overseeing animal research safety?
• What does OSHA stand for?
• What are three components that must be described in the Animal Welfare Assurance?
• Which of the following is NOT a category of Aquatic Life Support Systems?
• How is distress defined in the context of animal welfare?
• Which regulatory body does NOT mandate a scientific member on the IACUC?
• Should emergency veterinary care only be available during business hours?
• Which animals require the same minimum cage height recommendations in the Guide?
• Which of the following is NOT a component of the veterinary care program?
• What is the term for the immediate physical environment surrounding the animal in the primary enclosure?
• What is the purpose of the IACUC self-evaluation?
• What does the PHS Policy state about the use of the Guide for the Care and Use of Laboratory Animals by institutions receiving federal funding for research?
• Which studies require special consideration according to common practices?
• What must be included in the annual report to OLAW for PHS-assured institutions?
• For which scenario is veterinary consultation mandatory according to VA guidelines?
• Which behavior does NOT support effective IACUC protocol review?
• In the case of three or more designated reviewers, what is required for a decision to be made?
• What is the recommended procedure for removing soiled cages from a procedure room?
• Which of the following is NOT a responsibility of the attending veterinarian or designee?
• Regarding IACUC meeting attendance, which statement is false?
• When reporting an IACUC suspension of an animal activity, the IACUC should:
• How should personnel training in animal care programs be managed?
• The participation of personnel in Occupational Health and Safety Programs should be based on what factors?
• For which species is an adjunctive method of euthanasia recommended due to difficulty in detecting heartbeat?
• What is NOT one of the responsibilities of individual IACUC members?
• What virus causes a disease similar to smallpox but is less severe?
• If a PHS assured institution is not AAALAC accredited, what must be included in the annual report to OLAW?
• Are restraint devices considered a normal method of housing for animals?
• How often must the IACUC perform evaluations according to guidelines?
• How frequently does the PI need to reconsider alternatives?
• Which group monitors the conditions of procedure rooms?
• What should be done immediately after allegations of improper animal care are made?
• Which act is enforced by the USDA-APHIS-AC?
• What is primarily enforced by the Occupational Safety and Health Administration?
• What documents are mandated as the basis for the IACUC semi-annual evaluation?
• Which of the following does not represent a reduction in animal use?
• When should you seek agency advice regarding potential conflicts of interest?
• What term describes allergic reactions that occur within 10 to 15 minutes of exposure?
• What is a requirement for non-affiliated IACUC members?
• Who is primarily responsible for monitoring health and safety procedures in a laboratory animal program?
• Are room temperature settings for rodents typically set below their Lower Critical Temperature (LCT)?
• What is necessary for the IACUC to convene a meeting?
• Which of the following is NOT required when filing a PHS Institutional Assurance?
• For continuity in IACUC practices, which is essential for individuals involved?
• Which role is considered essential for all IACUC protocols and operations?
• Which of the following is not considered a hazardous property of a chemical?
• What role does the Institutional Official (IO) play in the evaluation process?
• For which of the following animals must health records be maintained?
• To whom is the semi-annual report submitted as per both AWAR and PHS Policy?
• How is a significant deficiency perceived in the context of animal trials?
• Which statement regarding polling IACUC members is TRUE?
• Which entity often uses the term "Attending Vet"?
• What types of protocols require administrative review and approval at the Component headquarters level in DoD research?
• Who has the authority to determine if a deficiency identified during an IACUC evaluation is significant or minor?
• What is the correct procedure regarding ACURO review and IACUC approval?
• If the IACUC suspends an activity, what is a primary responsibility of the IO?
• Which category of Aquatic Life Support Systems involves constant recycling of water?
• In research contexts, what does PI refer to?
• What fundamental role does an IACUC-approved PAM program serve?
• According to U.S. Government Principles, pain perceived by animals should be assumed in which situation?
• What accreditation is required by the VA?
• Can designated-member review be utilized for new submissions?
• Which procedure is correctly associated with Designated Member Review?
• Which statement about IACUC confidentiality is false?
• What is required of institutions concerning health history in occupational health programs?
• When the initial characterization of a GMA reveals a condition that negatively affects animal well-being, what should be reported to the IACUC?
• Animal Welfare Regulations for rabbits require:
• Which statement is false regarding the Occupational Health and Safety Program?
• Can animals remain in a lab until a protocol expires or they are euthanized?
• When designing a PAM program, which factors should be considered?
• According to USDA Regulations, how many members from one administrative unit can an IACUC have at maximum?
• In which of the following cases would an alternate member be allowed to vote?
• Which of the following does NOT need to be maintained by the IACUC?
• Notifying investigators of IACUC protocol review outcomes in writing is:
• Which regulatory body requires detailed three-year (triennial) reviews?
• According to USDA Regulations, an IACUC may have no more than how many members from any one administrative unit?
• What action should the IACUC take if an investigator mistakenly euthanizes animals using a method not approved in the protocol?
• What must the IACUC do to suspend an animal activity?
• For what purpose is maintaining gas flow for euthanasia after apparent death important?
• According to the PHS Policy, the definition of animal includes which of the following?
• For how long should records be kept according to PHS and AWRs?
• When must veterinary consultation occur?
• Which outcomes are recognized in IACUC protocol reviews according to regulations?
• Which classification system is primarily based on USDA pain/distress categories?
• What is required before conducting surgery regarding antinociception?
• What is the role of a non-affiliated member in the IACUC?
• Which role is typically not filled by an IACUC member?
• Which of the following is true regarding teleconferencing for IACUC meetings?
• Which official must approve changes to the animal care program?
• What requirement must be fulfilled before an animal can be used in research?
• What are used to standardize methods for performing specific institutional practices?
• Should facilities have a disaster plan for animals?
• According to the Guide, which statement is true regarding the use of non-pharmaceutical grade chemicals?
• The Guide for the Care and Use of Laboratory Animals states that those who care for or use animals must assume responsibility for what?
• What should an IACUC member do when they have a conflict of interest?
• Which of the following statements about IACUC suspensions of animal activities is false?
• What benefit does a formalized PAM program provide regarding compliance monitoring?
• Which statement is false regarding shigellosis?
• What is the typical minimum level of detail required in IACUC meeting minutes?
• When a federal employee licenses an invention to a private company, can they continue to work on that invention while on government duty?
• Which function is NOT typically performed by the IACUC?
• What is the main role of IACUC alternates?
• Which composition of members is required for an IACUC to comply with USDA Animal Welfare Act Regulations and PHS Policy?
• Which term is defined in the Guide as "an aversive state in which an animal fails to cope or adjust to various stressors with which it is presented"?
• What type of drug must be used with neuromuscular blocking agents?
• In the context of reheat coils in HVAC systems, what is the correct position for valves to fail?
• What defines a significant deficiency in the IACUC semi-annual report?
• Which term is defined as measures to control known or unknown infections in laboratory animals?
• True or False: The IACUC has no real authority to suspend animal activities.
• When conducting a semi-annual evaluation, how many IACUC members must be present?
• Which statement concerning IACUC suspensions is false?
• What are the recognized review methods by the USDA Animal Welfare Act and PHS Policy?
• Which function is not typically performed by the IACUC?
• How are protocols handled if designated members can neither all agree on approval nor modifications?
• How often must the IACUC conduct semiannual inspections?
• What training is not required for IACUC members according to the Guide?
• Which of the following is NOT a reason for formalizing a post-approval monitoring (PAM) program?
• What essential area must training and instruction provide guidance on for personnel?
• What is necessary for a biofilter to effectively process bioload?
• Personnel training and instruction must include guidance in which area?
• Although opinions vary about the level of detail needed in IACUC minutes, a typical standard is that IACUC minutes:
• Which of the following is crucial for effective IACUC protocol review?
• What happens to containment and safeguard practices as the BSL and ABSL levels increase from 1 to 4?
• In terms of refinement, which option does not qualify?
• If a grant is for longer than 3 years, can the triennial review period be extended?
• Which entity does not require the IACUC to have a scientific member?
• What is a required member type on the IACUC?
• Who must participate in the semiannual review of IACUC programs and facilities?
• What is the shelf life for feed that is fortified with non-stabilized vitamin C?
• Who must be notified of IACUC decisions to approve, withhold approval, or require modifications?
• What is the primary purpose of the IACUC's semi-annual evaluation?
• Which organization sets the regulations for the humane care and use of animals in research?
• Which of the following statements about the use of "alternate" IACUC members is false?
• What is not a recommended method to prevent Q fever infection in laboratory workers?
• What pressure should areas designated for surgery or clean equipment storage ideally maintain?
• What is the maximum weight for performing cervical dislocation on a rabbit?
• Who is authorized to conduct Post-Approval Monitoring (PAM)?
• What does AWA stand for?
• What is an ineffective way to identify hazards in a lab setting?
• Is the IO permitted to approve animal activities without IACUC approval?
• Can a regular IACUC member have multiple alternates?
• Which agency ensures that research involving animals is conducted ethically?
• Must chlorine and chloramines be removed before use in aquatic systems?
• According to VA policy, when using DMR, must all members receive complete copies of all protocol forms?
• What action must the institution take if notified by USDA of an investigation?
• What does DMR stand for in IACUC terminology?
• What is the maximum amount of extra caging that can be stored in a procedure room at one time?
• What is necessary when alternates participate in IACUC meetings?
• Which statement about IACUC membership is false?
• Which body can the IACUC consult when concerns about animal welfare arise?
• What is the organization whose guidelines on euthanasia are required by the PHS Policy?
• Which of the following statements is TRUE?
• Are alternates required to represent their regular members’ positions during voting?
• The acronym NRC is commonly known as what?
• If IACUC members have conflicts of interest, what is the best practice regarding protocol voting?
• When selecting a suitable social environment for animals, what two characteristics must be considered?
• When is the use of chemical restraint in animal studies permissible?
• Which statement about the responsibilities of the Institutional Official (IO) is incorrect?
• Can DoD researchers inflict wounds on animals for training purposes?
• What is a characteristic feature of Static Aquatic Life Support Systems?
• Which position holds the administrative authority to commit resources for animal care compliance?
• Following a semi-annual evaluation, how long does the IACUC have to address significant deficiencies?
• What is a characteristic of an effective veterinary care guide within a PAM program?
• What does AWAR/AWR stand for?
• Which agency requires the semi-annual evaluation of the IACUC?
• Who has the authority to approve a course of action following an IACUC investigation?
• What should the IACUC do when there are allegations of concerns regarding animal care and use?
• What organization does ACLAM represent?
• Which IACUC responsibility involves the suspension of activity not following approved protocols?
• How often must the IACUC review the animal care program and facilities?
• What is the required composition of IACUC members for compliance?
• Reports prepared by the IACUC during semiannual facilities inspections must distinguish between minor and significant deficiencies. Which of the following best describes a significant deficiency?
• What is required of institutions concerning animal welfare concerns?
• Are WOC (Without Compensation) employees covered by ethics statutes?
• What agency does NIH represent?
• Which of the following statements is false concerning prolonged restraint of animals?
• Can members of the IACUC hold more than one role at the same time?
• What is the recommended concentration of carbon monoxide used for euthanasia of small mammals?
• Do new forms have to be used for the triennial review?
• What role does the attending veterinarian play in IACUC activities?
• What is the purpose of the triennial review according to PHS Policy?
• Can a non-affiliated member receive compensation for their participation on the IACUC?
• Does distress always cause immediate observable changes in animals?
• Which statement accurately reflects the definition of expedited review within the context of IACUC?
• Which of the following statements accurately describes the importance of the IACUC?
• What critical factor requires special attention when utilizing decentralized research facilities?
• How is confirmation of death determined after euthanasia?
• In a DoD IACUC, what is the role of the veterinarian?
• What must be included in IACUC meeting minutes?
• Which statement regarding dermatomycosis is correct?
• According to AWAR, can any IACUC members be denied participation in the semi-annual evaluation?
• Which field does the American Association for Laboratory Animal Science focus on?
• When there is a change in the name of the institution or its ownership, how many days does the institution have to notify the APHIS AC Regional Director?
• Is there a requirement for the AV to pre-review protocols before IACUC submission in non-VA institutions?
• Who is ultimately responsible for the animal care and use program?
• What requirement does the Animal Welfare Act place on multiple survival surgery?
• Which of the following statements regarding performance standards is FALSE?
• What is a typical standard for IACUC minutes?
• Which of the following is an incorrect statement regarding regulations?
• Who does the IACUC notify upon finding deficiencies during their semiannual self-evaluation?
• What should the IACUC assess before allowing an animal activity to continue?
• What do the record-keeping requirements of the Animal Welfare Regulations specify about IACUC records?
• How is the IACUC's membership determined?
• Is emergency veterinary care required to be available after work hours and on holidays?
• Who is responsible for signing the Assurance?
• Who is typically defined as the CEO?
• How often should personnel who have contact with nonhuman primates be screened for tuberculosis?
• Do VA rules require that vet pre-review occur for all animal protocols before IACUC review?
• Who is referred to as the IO?
• Which outcome option is NOT available during designated review of animal protocols?
• Which of the following offers a voluntary accreditation program of institutional animal care and use programs?
• Post semi-annual evaluation, who must review and sign the report to comply with AWAR?
• How long is an IACUC approval valid for USDA covered species?
• Which animals are specifically excluded from the AWA?
• Which regulation is commonly considered regarding the use of fillable forms for animal protocols?
• What is a required member of the IACUC?
• Can a federal researcher represent a company licensing an invention in matters involving the U.S. government?
• What must the IO submit to the USDA/APHIS regarding major survival surgical procedures on regulated animals?
• What should the selection of analgesics and anesthetics reflect?
• Which two aspects are mandatory in Disaster Planning and Emergency Preparedness?
• Does the VA VMO have to be a full-time position?
• Which of the following statements about the USDA Animal Welfare Regulations and allegations of improper animal care is false?
• Which option best describes the IACUC's responsibilities?
• What action must be taken if an IACUC member learns about a potential violation of the Animal Welfare Act?
• What is required of all personnel involved in the care and use of animals in order to ensure high-quality science and animal well-being?
• Which regulation prohibits reprisal against individuals reporting violations in animal care?
• What percentage of royalty payments can federal employees receive from government-assigned inventions under the Federal Technology Transfer Act?
• Which of these IACUC protocol review outcomes is recognized in the USDA Animal Welfare Act Regulations and PHS Policy?
• What is a key benefit of utilizing designated-member review in IACUC protocols?
• Which statement best reflects the operation of an effective IACUC regarding minority opinions?
• What is one of the best practice credentials for an Attending Veterinarian?
• Which of the following details is not required in a narrative when conducting a database search for alternatives to painful animal procedures?
• Which statement about barbiturates is true?
• What is one requirement for the IACUC chair according to USDA regulations?
• Which statement regarding IACUC suspensions is false?
• The USDA Animal Welfare Regulations and PHS Policy emphasize the inclusion of which two components in the animal care evaluation?
• What action is not a duty of the IACUC during an investigation?
• According to OLAW, what is considered a suspension?
• Which organization enforces regulations pertaining to animal welfare in research environments?
• What is one objective of the annual report to the USDA/APHIS?
• How often should enclosures and accessories be sanitized at minimum?
• Which of the following is NOT a role of the attending veterinarian?
• What authority does the Attending Veterinarian have under AWAR?
• What does ILAR stand for?
• What should IACUC members do when they have a conflict of interest regarding a proposal?
• Can the CEO and the IO be the same individual?
• According to the PHS policy, any building, room, or area used for confinement, transport, or experiments including surgery is considered an animal facility if the animals are maintained there for more than ______ hours.
• Are chlorine and chloramines safe for use in aquatic systems without modification?
• What is the role of the Institutional Official (IO)?
• To violate Section 208, what must be true regarding the employee's financial interest?
• What is the correct protocol if a disaster occurs and animals cannot be relocated?
• Which of the following is typically not included in preventative medicine programs?
• Which statement regarding modifications to animal protocols after IACUC approval is TRUE?
• When reporting an IACUC suspension of an animal activity, what should the IACUC do?
• What is essential for conducting animal procedures causing pain or distress?
• If the IACUC votes to withhold approval, can it reconsider its decision?
• Under the Federal Technology Transfer Act, what is the maximum annual royalty payment an employee can receive for assigned intellectual property rights?
• What is a primary role of IACUC members during protocol discussions?
• What is a true statement regarding physical methods of euthanasia?
• Chloral hydrate is conditionally acceptable for euthanasia in large animals that are:
• According to the PHS Policy, can the non-affiliated member and the nonscientific member of the IACUC be the same person?
• Can both a member and their alternate contribute to a quorum simultaneously?
• Which statement regarding the investigation of complaints is true?
• What method is commonly used to monitor the effectiveness of an autoclave?
• What is considered best practice regarding institutional reporting practices?
• To comply with the law, who must review and sign the IACUC semi-annual self-evaluation report?
• Why is it considered better for the IACUC to have an odd number of members?
• Which of the following agencies is responsible for regulating food safety?
• Which statement is TRUE about exercise plans for dogs?
• Are alternate members allowed to attend IACUC meetings when their regular counterparts are present?
• What kind of corrective actions is the Component headquarters responsible for overseeing?
• Which regulatory body is primarily responsible for enforcing animal welfare standards in the U.S.?
• What is particularly important for IACUC members serving as the lay member or the non-affiliated member?
• Which mandate requires occupational health services for employees in animal facilities?
• What does the acronym APHIS stand for?
• How long must research institutions retain certain records for possible review after the completion of a project?
• Which of these statements is true concerning the USDA Animal Welfare Act?
• Who is responsible for ensuring that personnel working with live animals are properly trained?
• Which of the following best describes how minority opinions should be recorded?
• What is the minimum number of voting members required for the IACUC?
• What action must be taken when using chlorine in aquatic systems with animals?
• What best practice should an IACUC follow when addressing concerns about animal care?
• Which group of animals is primarily covered by the USDA/AWA?
• What is a necessary condition for an institution to notify the Component headquarters?
• Do individual members of the IACUC have the authority to stop animal activities?
• What does "suspension" mean in the context of animal activities?
• The IACUC may suspend an activity only after what condition has been met?
• What is a regulation?
• Which document governs the humane care of animals in research according to these regulations?
• What does Post Approval Monitoring entail?
• What is a true statement about routes of administration for injectable agents?
• In a research environment, why is it important to quarantine before or after using specialized research areas?
• Under which circumstance may animal work commence before IACUC approval is received?
• Which organization is responsible for conferring CPIA certification?
• Life support systems are usually one of three types: re-circulating, flow-through, or ____________________.
• Which US agency requires placing animals used in research into pain/distress categories?
• Which of the following statements about OLAW's guidance on the use of carbon dioxide as a euthanasia agent is false?
• How often must the IACUC perform an annual review of a protocol?
• Which statement regarding the responsibilities of the Institutional Official (IO) is false?
• Which organization is referred to as the CDC?
• What is not required by Animal Welfare Regulations for transport cages?
• What does FASS stand for in the context of animal science?
• What is the correct procedure regarding IACUC member voting?
• Which policy states that IACUC members may not contribute to a quorum when reviewing their own protocols?
• Which statement is TRUE regarding health requirements for shipping animals?
• What key information must be included in an IACUC semi-annual self-evaluation report regarding deficiencies?
• What space requirements for cats are included in the Animal Welfare Regulations?
• How strict are the annual and triennial deadlines for protocol reviews?
• Single housing of social species should be justified by what criteria?
• Notifying investigators of IACUC protocol review outcomes in writing is:
• Which of the following statements about minority opinions in IACUC meetings is correct?
• What statement accurately describes an active PAM program?
• What is the maximum amount a federal employee’s family can own in a sector mutual fund to recommend purchasing drugs from a pharmaceutical company?
• What is the implication of the term “conditional approval” in the context of IACUC reviews?
• Which of the following is true about IACUC member training?
• To which animals do VA rules apply?
• When conducting a semi-annual evaluation, what is the minimum number of IACUC members required to be present?
• When selecting proper equipment for facilities, which of the following should not be a primary consideration?
• What consequence can arise from a member not disclosing a conflict of interest?
• What is the first step in a designated IACUC review?
• Which of the following is not an example of replacement in animal research?
• Record-keeping requirements of the Animal Welfare Regulations state that:
• Which of the following statements about IACUC confidentiality is false?
• What document does the USDA require to be used as the basis for the semi-annual evaluation?
• What action should be taken following the suspension of an animal activity by the IACUC?
• Which aspect of facility design is emphasized in the Guide for animal care?
• DoD rules apply to which type of animals?
• Which regulation ensures that veterinary care is provided even when an attending veterinarian is unavailable?
• According to VA rules, who is mandated to serve as the Institutional Official (IO)?
• Which of the following is the best definition of a laboratory animal?
• What is the primary purpose of the IACUC?
• How should euthanasia agents that induce hypoxia be viewed in regards to certain animal groups?
• Which area must personnel training and instruction cover?
• If a VA researcher conducts research after hours, can a VA non-profit research corporation supplement the employee's salary for the work?
• How should hazardous wastes be handled before removal from the facility?
• What is the primary action by which physical methods of euthanasia cause death?
• How many members of the IACUC can come from the same administrative unit according to USDA regulations?
• Which of the following is not a recordkeeping requirement according to PHS?
• What are the two categories of deficiencies reported in the semi-annual report?
• Which agency regulates the use of radioisotopes?
• What is the principal danger of using inhalation agents for euthanasia?
• What is the main purpose of performance standards in compliance regulations?
• Who are essential voting members of the IACUC?
• What is the maximum amount of time the IACUC has to report a failure to correct significant deficiencies to the USDA?
• To conduct official business in a meeting, a quorum of voting members must:
• Can an IO suspend IACUC approved activities?
• What is the minimum number of members required for a DoD IACUC?
• What happens if designated reviewers have differing opinions on modifications required for approval?
• Is it acceptable to immerse aquatic species in carbon dioxide for euthanasia?
• Who has the authority to assign designated reviewers when designated-member review is applied?
• The three Rs of Russell and Burch promote which principles in research?
• What happens if a PI fails to complete the triennial review by the deadline?
• Can a non-affiliated member of the IACUC be a scientist?
• Before the meeting, do IACUC members need access to full protocols?
• What is required in Animal Welfare Regulations for housing guinea pigs and/or hamsters?
• What defines a quorum for IACUC meetings?
• Which action is NOT permitted by the IO according to Animal Welfare Regulations and PHS policy?
• Institutions should use the recommendations in the Guide as what?
• Which reporting line does OLAW recommend for an animal care and use program?
• Is the authority to stop animal activities exclusive to the IACUC?
• What is a typical responsibility of the Attending Veterinarian concerning necropsies?
• Whom does the IACUC make recommendations about the animal program to?
• How long can approval be maintained for non-USDA covered species?
• Who has the authority to approve amendments to protocols involving specific animal types in DoD research?
• Which regulatory body's guidelines are followed for maintaining an effective IACUC?
• What is a critical aspect regarding the use of primary reviewers?
• What does the acronym IRAC stand for in the context of animal research?
• True or False: According to the 2011 Guide, a Chair is considered an essential member.
• What is critical for animal welfare when assessing their environment in research?
• Which statement about laboratory requirements is false?
• Are alternate members specifically addressed within AWAR or PHS Policy?
• What should be avoided in an animal's resting area within an enclosure?
• What is one of the primary responsibilities of the IACUC?
• Which of the following is an example of a record that is NOT required by the IACUC to maintain?
• Euthanasia agents that act by way of hypoxia are not recommended for which type of animals?
• Which document outlines policies regarding the care and use of laboratory animals?
• Which statement about restraint devices in animal care is true?
• Which of the following must be part of the corrective action plan for deficiencies?
• What does the Ag Guide refer to?
• What is a permissible outcome of a full committee review (FCR)?
• According to the Ag Guide, which is not a requirement for IACUC membership?
• How frequently does the USDA conduct inspections of research facilities?
• What must animals have in a primary enclosure setup?
• Who is responsible for appointing members to serve on the IACUC?
• When reporting an IACUC suspension, what is the appropriate action?
• What is the primary goal of the Guide for the Care and Use of Laboratory Animals?
• What is the minimum number of designated reviewers required for a protocol using designated-member review?
• Which of the following information need not be present on an official tag?
• What is necessary for significant changes to animal protocols after IACUC approval according to policy?
• What happens if the IACUC decides to suspend an activity?
• What kind of training must IACUC members undergo according to the Guide?
• What is the main problem caused by algae growth in an aquatic system?
• What is the primary purpose of the Animal Care Section of the USDA?
• Are designated members allowed to withhold approval for a protocol?
• Is it necessary for VA employees to have prior permission for outside financial ventures?
• Which of the following statements is true regarding review outcomes in full committee review versus designated review of animal protocols?
• Which of the following documents is included in the PHS Institutional Assurance filing requirement?
• Why are inspections of animal use areas important in a PAM program?
• Which of the following best describes the role of the Institutional Official (IO) in animal research?
• Who is responsible for signing the USDA/APHIS Annual Report?
• When an institution uses agricultural animals, what is a requirement for IACUC membership?
• The institution's program for the care and use of animals should include which of the following information?
• What is the relationship between a VA IACUC and an affiliate IACUC?
• Must a non-affiliated member be present for the IACUC to conduct its business?
• What options do IACUCs have if additional information is provided by a PI after a decision to withhold approval?
• Who should you discuss potential outside payment and royalty opportunities with to protect yourself from penalties?
• Which regulations must Department of Defense (DoD) researchers adhere to?
• What is the purpose of a semiannual review by the IACUC?
• Which statement regarding required IACUC members is false?
• What is the consequence of failing to disclose conflicting financial interests?
• Who has the authority to determine the time frame for requesting a full committee review (FCR)?
• Which entity generally oversees the process of ensuring compliance with animal welfare standards in research facilities?
• If a compliance incident involves USDA-covered animals, what must be reported to the USDA?
• What is the minimum duration that records must be retained in DoD research?
• Can the IACUC suspend animal activities that it has never reviewed?
• How detailed should the PHS-required three-year review be?
• What type of identification is not acceptable for dogs or cats at acquisition?
• During a euthanasia procedure, if an animal exhibits a reflex movement, what does it indicate?
• Are significant deficiencies required to be reported to regulatory bodies immediately?
• What does ACLAM stand for?
• Which of the following is NOT a responsibility of the IACUC?
• Which of the following members is required in a PHS-compliant IACUC?
• True or False: The AWAR provides protections for whistleblowers who report violations.
• Why is appropriate training crucial for researchers conducting surgeries?
• The failure position of valves controlling reheat coils is designed to promote what condition?
• What is the minimum requirement for access to drinking water for animals?
• Who is primarily responsible for developing a useful occupational health program?
• What activity would disqualify an animal from USDA category B?
• Which of the following roles is NOT specified by USDA AWAR?
• Can amendments just wait until the annual review?
• What is not a best practice for IACUC members?
• When might an employee need to disclose financial interests according to conflict of interest policies?
• What record must be kept by research facilities according to USDA Regulations?
• According to PHS policy, how often must assurance renewal occur?
• What is the benefit of using physical methods over non-physical methods for euthanasia?
• Which statement regarding floor drains is true?
• To comply with the USDA Animal Welfare Act Regulations, what is the proper IACUC course of action to follow if a significant deficiency is not corrected according to the plan set forth in the IACUC semi-annual evaluation report?
• Why is monitoring of dry-bulb temperatures critical in HVAC systems?
• What must occur within 5 business days according to DoD regulations when certain events happen?
• In outdoor housing, should animals have protection from harsh weather conditions?
• What allows for the loss of AAALAC accreditation according to the provided context?
• Which of the following statements regarding mouse allergen is true?